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According to the organizers of this NIH-funded international “Family Study of Affective and Anxiety Spectrum Disorders” – ClinicalTrials.gov # NCT00071786:

• It will examine how depression, anxiety, and migraine run in families. It will help in defining the risk factors for physical, mental, and health problems - as well as define ways that those problems may be prevented and treated.
• A broad range of ages among family members will be included to evaluate the patterns of how these disorders are expressed throughout people's lives. Children of all ages will be included, and those ages 8 to 17 will be interviewed directly.
• A member of the study team will visit the participants at home or will do an interview by telephone to collect information.
• Participation will take approximately 3 to 4 hours.
• Children will complete questionnaires given by the research team as well as questionnaires that they will do by themselves. The questions will pertain to the children's health, including physical and mental health and medical history, social relationships, problems, skills, and ways of dealing with important or stressful issues in their lives. These questionnaires will take up to 1 hour to complete.
• Health history gathered from adult participants will pertain to height, weight, exercise, and general function. Women will be asked about the use of oral contraceptives, estrogen, and progesterone. In addition, there will be questionnaires on personality and temperamental traits, that is, behavior and impulsiveness.
• Questions will also involve social intuition, family and other environmental factors, general functioning, and basic demographics such as ethnicity, race, socioeconomic status, marital status, education level, and employment history.
• Families enrolled in this phase of the research will be invited to participate in the next phase. There would be follow-up to evaluate the development of mood disorders, subtypes, and syndromes across the lifespan.

Recruiting Centers are located in the US, Canada, China, and Switzerland.

For more information and to review inclusion/exclusion criteria, see the study’s ClinicalTrials.gov listing http://www.clinicaltrials.gov/ct2/show/NCT00071786

Contact Information:
National Institutes of Health Patient Recruitment and Public Liaison Office
(800) 411-1222
prpl@mail.cc.nih.gov
Mention study title “Family Study of Affective and Anxiety Spectrum Disorders,” and number NCT00071786